Early-onset cancer incidence increased 3% globally during the past 3 decades, but mortality from these malignancies dropped 17%.“It’s good news,” Rupayan Kundu, MD, resident physician at Cleveland Clinic, told Healio, comparing the “subtle” increase in diagnoses with the significant reduction in deaths.However, obesity remains a substantial concern in early-onset disease, as mortality related to high BMI increased nearly 93% between 1990 and 2021.“There is a global epidemic in obesity, and we are seeing the effect right now,” Kundu said.Early-onset cancer has become a focus of extensive