Key Takeaways • Sean Ianchulev, MD, MPH, will present miDOC at the upcoming ASCRS Annual Meeting • The investigational system is designed to provide continuous intraoperative measurements of ocular flow and pressure • Early clinical use of the technology at New York Eye and Ear Infirmary of Mount Sinai has been promising Sean Ianchulev, MD, MPH, a professor of ophthalmology at the Icahn School of Medicine at Mount Sinai and the director of ophthalmic innovation and technology at New York Eye and Ear Infirmary of Mount Sinai (NYEE), plans to unveil miDOC (microinterventional dynamic outflow curve) during the Charles D. Kelman Innovator’s Lecture at the ASCRS Annual Meeting in Washington, DC, on April 12, 2026. Developed by Dr. Ianchulev at NYEE with funding from Mount Sinai Innovation Partners, miDOC is designed to provide continuous intraoperative measurements of ocular flow and pressure—parameters that have been difficult to assess during surgery. The system reportedly enables surgeons to monitor changes in real time and adjust procedures accordingly for each patient. "This is the equivalent of what optical biometry did for cataract surgery,” says Dr. Ianchulev. “miDOC brings precision to glaucoma surgery that simply has not existed before. We are certainly on the verge of something very exciting—bringing glaucoma surgery into the age of digital-guided precision, high fidelity, and biometric feedback. This will allow glaucoma surgeons to one day achieve similar outcomes as we see in cataract surgical interventions.” NYEE is the only eye center in the country to use the technology and conduct the first-in-human clinical study, per the press release. Surgeons started using it in patients in July 2025 and have reportedly completed the first 20 cases. According to investigators, all procedures were successfully completed with intraoperative biometric guidance. During surgery, miDOC reportedly enabled continuous measurement of the following parameters: pressure, flow, outflow facility, and ocular rigidity/compliance. These measurements reportedly provide insight into how surgical interventions affect the eye in real time. “Intraoperative measurement of aqueous outflow has not previously been possible during ophthalmic surgery,” says Gautam Kamthan, MD, an assistant clinical professor of ophthalmology at the Icahn School of Medicine and assistant director of ophthalmic innovation and technology at NYEE, who coinvented the technology and is the principal investigator of the study. “This capability has the potential to transform outflow-based surgical interventions by advancing the field toward high-precision biometry and improved clinical outcomes,” According to the press release, while initially developed for glaucoma surgery, miDOC might have broader applications in ophthalmology. Researchers are also reportedly exploring whether the system could provide insights into cerebrovascular, cardiac, and lymphatic physiology. Investigators at NYEE plan to refine the technology and pursue regulatory pathways for broader clinical use. The device is currently investigational and has not yet received FDA clearance.